n of 1 trials – paracetamol

Single patient trials (SPT) of paracetamol for pain in palliative care patients on regular opioids

This trial examines the feasibility of aggregating multiple SPTs to gain a population estimate of the efficacy of paracetamol in pain where the patient is on regular opioids.

Current status:

Funded, completed

Recent publications:

Single-patient multiple crossover studies to determine the effectiveness of paracetamol in relieving pain suffered by patients with advanced cancer taking regular opioids: A pilot study The Essential Guide to N-of-1 Trials in Health

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